Iron Oxide-Gold Core-Shell Nanoparticles and Uses Thereof | The method lead to the products of magnetic-optical iron oxide-gold core-shell nanoparticles in sphere, oval, flower, star and pin shapes and absorption wavelength. No current competitive/available alternatives that make this technology applicable in a wide range of areas including energy conversion, catalysis, biological separation, cancer detection and treatment | 9952209 |
Methods for producing a biodegradable chitosan composition and uses thereof | The invention provides improved methods for generating biodegradable chitosan compositions, and therapeutic methods of using such compositions to deliver therapeutic agents. | 9662400 |
Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes that can potentially reduce generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8969590 |
Pipemidic Acid Derivative Autotaxin Inhibitors | The technology is about optimizing classes of pipemidic acid derivative compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8497371 |
Biomaterial Composite Compostion And Method of Use | This invention relates to a process to facilitate osteochondral bone remodeling in a subject by inducing regeneration of this bone to a healthy, vascularized state capable of supporting the underlying hyaline cartilage of articular joints and spinal discs, both biomechanically and metabolically and to deliver a bioactive agent. | 8404256 |
Diverse Lead Compound Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8343934 |
Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8268891 |
Mechanism-Based Inactivators of Autotaxin | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8022239 |
Chitosan nanofiber compositions, compositions comprising modified chitosan, and method of use | This invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included. | 20160367722 |