| Iron Oxide-Gold Core-Shell Nanoparticles and Uses Thereof | The method lead to the products of magnetic-optical iron oxide-gold core-shell nanoparticles in sphere, oval, flower, star and pin shapes and absorption wavelength. No current competitive/available alternatives that make this technology applicable in a wide range of areas including energy conversion, catalysis, biological separation, cancer detection and treatment | 9952209 |
| Methods for producing a biodegradable chitosan composition and uses thereof | The invention provides improved methods for generating biodegradable chitosan compositions, and therapeutic methods of using such compositions to deliver therapeutic agents. | 9662400 |
| Polymer Nanocapsules Entrapping Metal Nanoparticles | The invention is about the methods of making and using the metal nanoparticles entrapped or encapsulated in a polymer nanocapsule. | 9248441 |
| Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes that can potentially reduce generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8969590 |
| Nanothin Polymer Fims With Selective Pores and Method of Use Thereof | A method of preparing nanothin polymer films having uniform and selectively sized pores utilizing pore forming templates. The guided assembly method presented here suggests a new general strategy for the fabrication of nanothin materials with controlled permeability, which provides improvements over the currently existing technology. | 8519015 |
| Pipemidic Acid Derivative Autotaxin Inhibitors | The technology is about optimizing classes of pipemidic acid derivative compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8497371 |
| Biomaterial Composite Compostion And Method of Use | This invention relates to a process to facilitate osteochondral bone remodeling in a subject by inducing regeneration of this bone to a healthy, vascularized state capable of supporting the underlying hyaline cartilage of articular joints and spinal discs, both biomechanically and metabolically and to deliver a bioactive agent. | 8404256 |
| Diverse Lead Compound Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8343934 |
| Autotaxin Inhibitors | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8268891 |
| Mechanism-Based Inactivators of Autotaxin | The invention is about classes of compounds that exhibit effective inhibition of autotaxin enzymes. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. | 8022239 |
| Nanothin Polymer Coatings Containing Thiol and Method of Use Thereof | The present invention provides a new monomer and methods of using the monomer to fabricate robust polymer surface coatings. The coating provides complete surface coverage, is extremely robust, and exhibits excellent insulating and anti-corrosive properties. | 7829155 |
| Nanothin Polymer Films With Selective Pores and Method of Use Thereof | A method of preparing nanothin polymer films having uniform and selectively sized pores utilizing pore forming templates. The guided assembly method presented here suggests a new general strategy for the fabrication of nanothin materials with controlled permeability, which provides improvements over the currently existing technology. | 7678838 |
| Fully Reconfigurable Modular Body-Worn Sensors | This invention is a sensor level modular and fully reconfigurable EEG system along with other body-worn sensors that will allow Lego-like connectivity of multi-modal sensors on the body. this is achieved by elimination of the DRL circuit from the traditional EEG (and ECG) circuit design with a new analog front end design that is independent for each channel. Consequentially, a system is envisioned where the number of EEG channel (sensor nodes) can be one or many, independent of the design, and can be customized at the time of deployment in a Lego-Like fashion. Subsequently, such system can incorporate any type of body worn sensors with the network. Additionally, the sensors can be equipped to perform some computation on the local sensor data that will enable distributed intelligence. The outcomes will enhance capabilities of neurological and physiological data collection at natural environments | 10973430 |
| Chitosan nanofiber compositions, compositions comprising modified chitosan, and method of use | This invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included. | 20160367722 |
