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Faculty and Staff Profiles |
Esra Roan |
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Office Location: |
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Honors/Awards
- Outstanding Paper by A Junior Investigator - AJP Lung (American Physiological Society) - 2014
- Member of the Athletic Hall of Fame - Tennessee Technological University - 2011
- Summer Graduate Internship - University of Cincinnati - 2004
- Varsity Tennis Scholarship - Tennessee Technological University - 1994-1998
- Pi Tau Sigma - Tennessee Technological University - 1997
Teaching Experience
- Machine Design 3 - University of Memphis
- Applied Finite Element Analysis (BIOM4/6393,MECH4/6393) - University of Memphis
- Engineering Design - University of Memphis
- Engineering Materials (MECH3320) - University of Memphis
Student Advising/Mentoring
- PhD Mechanical Engineering - Jie Gao - 2014
- MS Biomedical Engineering - Corey Holt - 2014
- MS Biomedical Engineering - Adetoun Komolafe - 2014
- MS Biomedical Engineering - Thien Phung - 2013
- MS Biomedical Engineering - Hummad Tasneem - 2014
- MS Mechanical Engineering - Manish Barlingay, Unversity of Cincinnati (Committee Member) - 2012
- MS Mechanical Engineering - Tirthankar Bhattacharjee, University of Cincinnati (Committee Member) - 2010
- PhD Biomedical Engineering - Gabriel Rapalo (Co-Mentor, Dr. C.M. Waters, UTHSC) - 2013
- MS Biomedical Engineering - Angela Zhang (Co-Mentor, Dr. Weikan Gu, UTHSC) - 2012
- BS Biomedical Engineering - Hummad Tasneem - 2011
- BS Biomedical Engineering - Thien Phung - 2011
- MS Biomedical Engineering - Alex Bada - 2011
- MS Mechanical Engineering - Meagan Buechel - 2011
- BS Biomedical Engineering - Cynthia Chapman - 2010
- MS Biomedical Engineering - Egleide Elenes - 2010
- MS Biomedical Engineering - Cathy Cozad - 2010
- MS Mechanical Engineering - Aditya Patel - 2008
Support
- Hernia Mesh Repair Using Various Fixation Techniques - UTHSC (BARD) - $37,514 - 13-14
- K01: TNF-a induced increase in alveolar epithelial stiffness and lung injury. - NIH K01 HL120912 - $764k - 13-18
- Mechanobiology of Tight Junctions in ARDS - American Thoracic Society - $40,000 - 13-14
- Mechanotransduction of Alveolar Epithelial Cells - UTHSC (NIH) - $144,449 - 09-13
Journal Articles
- Zhang, Y., Huang, J., Jiao, Y., David, V., Kocak, M., Roan, E. , ... & Gu, W. (2015). Bone Morphology in 46 BXD Recombinant Inbred Strains and Femur-Tibia Correlation. The Scientific World Journal, 2015.
- Roan, E., Waters, C. M., Teng, B., Ghosh, M., & Schwingshackl, A. (2014). The 2-Pore domain potassium channel TREK-1 regulates stretch-induced detachment of alveolar epithelial cells. PloS ONE, 9(2), e89429.
- Gao, J., Williams, J. L., & Roan, E. (2014). On the state of stress in the growth plate under physiologic compressive loading. Open Journal of Biophysics, 4, 13.
- Wilhelm, K. R.*, Roan, E.*, Ghosh, M. C., Parthasarathi, K., & Waters, C. M. (2014). Hyperoxia increases the elastic modulus of alveolar epithelial cells through Rho kinase. FEBS Journal, 281(3), 957-969. *Equally contributed.
- Stoikes, N., Sharpe, J., Tasneem, H., Roan, E., Paulus, E., Powell, B., Webb, D., Handorf, E., Eckstein, E. & Voeller, G. (2013). Biomechanical evaluation of fixation properties of fibrin glue for ventral incisional hernia repair. Hernia, 1-6.
- Bhattacharjee, T., Barlingay, M., Tasneem, H., Roan, E., & Vemaganti, K. (2013). Cohesive zone modeling of mode I tearing in thin soft materials. Journal of the Mechanical Behavior of Biomedical Materials, 28, 37-46.
- Roan, E., Wilhelm, K., Bada, A., Makena, P. S., Gorantla, V. K., Sinclair, S. E., & Waters, C. M. (2012). Hyperoxia alters the mechanical properties of alveolar epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology, 302(12), L1235.
- Qiu, N., Xiao, Z., Cao, L., Buechel, M. M., David, V., Roan, E., & Quarles, L. D. (2012). Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia. Journal of Cell Science, 125(8), 1945-1957.
- Roan, E. and Waters, C.M. "What do we know about mechanical strain in lung alveoli?" American Journal of Physiology: Lung Cellular and Molecular Physiology, 301: L625-635.
- Waters, C. M., Roan, E. and Navajas, D. 2012. "Mechanobiology in lung epithelial cells: measurements, perturbations, and responses". Comprehensive Physiology. 1–29.
- Roan, E. and Vemaganti, K. "Strain rate-dependent viscohyperelastic constitutive modeling of bovine liver tissue". Medical & Biological Engineering & Computing: Volume 49, Issue 4 (2011), Page 497.
- Roan, E. The effect of Glisson’s capsule on the superficial elasticity measurements of the liver. Journal of Biomechanical Engineering, 132(10):104504, 2010.
- Roan, E., Bada, A., and Buddington, R. "Mechanical characterization of preterm neonate pig liver as a function of high-density lipoprotein (HDL)". In Proceedings of the IMECE2010, Vancouver, BC.
- Elenes, E.Y., Roan, E., Janda, H., Marinescu, R. "Mechanical validation of a composite hemipelvis model using finite element analysis". In Proceedings of IMECE 2010, Vancouver, BC.
- Wagh, A.A., Roan, E., Chapman, K.E., Desai, L.P., Rendon, D.A., Eckstein, E.C., Waters, C.M. Localized elasticity measured in epithelial cells migrating at a wound edge using atomic force microscopy. Am J Physiol Lung Cell Mol Physiol, 295(1):L54–60, 2008.
- Roan, E. and Vemaganti, K. The nonlinear material properties of the liver tissue determined from no-slip uniaxial compression experiments. Journal of Biomechanical Engineering, 129:450–456, 2007.
- Rapalo, G., Roan, E., Schwingshakl, A., Eckstein, E., & Waters, C. (2014). Stimulation of mitochondrial superoxide in lung epithelial cells using a novel stretching device (869.5). The FASEB Journal, 28(1 Supplement), 869-5.
- Wilhelm, K., Roan,E. , Waters, C.M. "Hyperoxia increases elastic modulus of alveolar epithelial cells through Rho kinase". Experimental Biology 2012, San Diego, CA.
- Roan, E., Wilhelm, K., Bada, A., Makena, P.S., Gorantla, V.K., Sinclair, S.S., Waters, C.M. "Alveolar epithelial cells exposed to hyperoxia exhibit a stiffer mechanical response". Am. J. Respir. Crit. Care Med. 183: A2103.
- Roan, E., Haden, J., Elenes, E., Marinescu, R. Gender bias in pelvic fractures: a geometrical and structural assessment. ASME SBC, Keystone, CO (2009).
- Roan, E. et al. Force spectroscopy of primary alveolar epithelial type II cells, Society of Engineering Science, 45th Annual Meeting, Urbana, IL (2008).
- Roan, E. and Vemaganti, K. "Viscohyperelastic modeling of the liver tissue". Summer Bioengineering Conference, Marco Island, FL (2008).
- Roan, E. and Vemaganti, K. An approach to extract material parameters from no-slip uniaxial compression experiments on soft tissue. 7th World Conference of Computational Mechanics, Los Angeles, CA (2006).
- Vemaganti, K. and Roan, E. Multi-scale modeling of the mechanics of liver tissue. SES, University Park, PA (2006).
- Roan, E. Rajic, S. and Datskos, P. Optically actuated all optical mechanical switch. In Lasers and Electro-Optics Society 2000 Annual Meeting. LEOS 2000. 13th Annual Meeting. IEEE, volume 2, pages 641 –642 vol.2, 2000.
Presentations
- Mechanics of Cells Seminar Series in the Life Sciences Department, University of Memphis, (2012).
- "Hyperoxia increased the elastic modulus of alveolar epithelial cells" Biomedical Engineering Society, Hartford, CT (2011).
- "Mechanical properties of migrating cells" Experimental Biology, San Diego, CA (2012).
- "Mechanobiology of Alveolar Epithelial Cells", School of Dynamic Systems, University of Cincinnati, Cincinnati, OH (2011).
- "Lung Biomechanics and Alveolar Strain Field" Invited Seminar at UTHSC Physiology Department, Memphis, TN (2010).
- "Biomechanics of Soft Biological Materials", SWE Regional Conference, University of Memphis (2010).
- "Sex Bias in Pelvic Fractures", Memphis Bioworks Invitation that is cancelled due to weather, but presented at UM/UTHSC seminar series, Memphis, TN (2010).
- "Soft Tissue Biomechanics: Mechanical Characterization of Liver and Pulmonary Alveolar Mechanics" Koc University College of Engineering Seminar Series, Istanbul, TUR, (2009).
- "Biomechanics of the Liver Tissue" UTHSC Pharmacology Seminar Series, Memphis, TN (2008).
- An approach to extract material parameters from no-slip uniaxial compression experiments on soft tissue. 7th World Conference of Computational Mechanics, Los Angeles, CA (July, 2006).
- "Biomechanics of the Liver Tissue" Smith and Nephew, Memphis, TN (2007).
- "Biomechanics of the Liver Tissue" UTHSC/UM Biomedical Engineering Seminars, Memphis, TN (2007).
- Multi-scale modeling of the mechanics of liver tissue. Society of Engineering Science, University Park, PA (2006).
- "Viscohyperelastic Modeling of the Liver Tissue". Summer Bioengineering Conference, Marco Island, FL (2008).
Appendix A - Teaching Experience
- MECH3320 - Engineering Materials
- MECH3320 - Engineering Materials
- MECH3320 - Engineering Materials
- MECH4323 - Machine Design 3
- MECH4323 - Machine Design 3
- MECH3320 - Engineering Materials
- MECH4393/6393 - Applied Finite Element Analysis
- MECH3320 - Engineering Materials
- MECH4323 - Machine Design 3
- MECH4393/6393 - Applied Finite Element Analyses
- MECH4323 - Machine Design 3
- MECH3323 - Engineering Materials (w/ Honors)
- MECH4393/BIOM4393/ME - Applied Finite Element Analyses
- MECH4350/6350 - Biomechanics
- MECH4393/BIOM4393/ME - Applied Finite Element Analyses
Appendix D - Support
- Hernia Mesh Repair Using Various Fixation Techniques
Role: PI (Sub), Sponsor: UTHSC-Industry, Amount: $37,514, Period: 13-14, Status: Funded.
- ATS Early Recognition: Mechanobiology of Tight Junctions in Alveolar Epithelial Cells in ARDS
Role: PI, Sponsor: ATS, Amount: 39,965, Period: 13-14, Status: Funded.
- K01: TNF-a induced increase in alveolar epithelial stiffness and lung injury
Role: PI, Sponsor: NIH-NHLBI, Amount: 736,582, Period: 13-18, Status: Funded.
- Mechanotransduction of Acute Lung Injury
Role: PI (Sub), Sponsor: UTHSC (NIH), Amount: 144,449, Period: 09-13, Status: Funded and completed.
- K25: Mechano-biology of Cell-to-cell Junctions
Role: PI, Sponsor: NIH, Amount:$766,929, Period: 12-17, Status: Not funded, scored 31.
Appendix E - Outreach
- Reviewer for AJP: Lung Cellular and Molecular Physiology
- Facebook Page Administrator for the Biomedical Engineering (2014-Present).
- Reviewer for Journal of Biomechanics
- Reviewer for Journal Biomechanical Engineering
- Reviewer for Engineering in Medicine
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